An overnight stay in Istanbul sets the tone, providing time for deliberate exploration of all the landmark attractions, including the Hagia Sophia, a Byzantine marvel that has been a cathedral, mosque and now museum. History buffs will revel in the chances to ramble among Greek ruins, scattered about in places such as the Hellenic acropolis on Rhodes and on Delos, home to three temples dedicated to Apollo. While Italy also has its share of ancient sites, such as world-famous Pompeii and Herculaneum near Sorrento, there is also an abundance of contemporary diversions. Spend an afternoon in a seaside café in Positano. Shop for handmade jewelry in the boutiques of Taormina. And during an overnight stay in Venice, board a vaporetti and skirt from island to island or venture to Murano and shop for glass masterpieces.

Prices (based on cruise-only)

Penthouse (PH1-3) - £1,808

Veranda (B1-B2) - £1,608

Outside (C/D) - £1,408

Inside (F/G) - £1,208